Conditions We Treat
CARPAL TUNNEL SYNDROME
At a glance
Carpal tunnel syndrome occurs when the median nerve is compressed as it passes through a narrow tunnel at the front of the wrist. It causes numbness, tingling and weakness in the thumb, index, middle and half the ring finger, classically waking you at night. It is the most common nerve compression condition in the body, affecting roughly 3 to 6% of adults. Most mild to moderate cases respond well to conservative treatment: a 2024 Cochrane review found surgery probably offers no clinically important advantage over splinting, and a 2025 network meta-analysis of 49 trials ranked manual therapy the most effective conservative option for pain.
If you wake in the night with a hand that feels dead, swollen or full of pins and needles, and you find yourself hanging it over the side of the bed or shaking it to bring it back to life, you are describing carpal tunnel syndrome almost exactly. That night-time pattern is the most reliable clue there is.
The carpal tunnel is a narrow passage on the palm side of your wrist. Its floor and walls are formed by the small carpal bones and its roof by a tough band of connective tissue. Nine tendons and one nerve pass through it. There is very little spare room, so anything that increases the pressure inside, whether swelling of the tendon sheaths, fluid retention or thickening of the tissue, compresses the median nerve. That nerve supplies sensation to the thumb, index finger, middle finger and half the ring finger, which is why symptoms follow that specific pattern and spare the little finger.
It is often assumed to be a typing injury. Heavy repetitive or forceful hand use certainly contributes, but the strongest risk factors are systemic. Pregnancy is a common trigger through fluid retention. Diabetes roughly doubles the risk, and an underactive thyroid, rheumatoid arthritis and a higher body weight all raise it. It is more common in women and becomes more likely after 50. Understanding which of these applies to you changes what treatment should target, and it is a large part of why two people with identical symptoms can need quite different plans.
Diagnosis is primarily clinical. A careful history and examination, including tests that briefly provoke the symptoms and an assessment of sensation and grip strength, identify most cases. Nerve conduction studies are useful when the picture is unclear, when symptoms could be coming from the neck or when surgery is being considered, because they grade how severely the nerve is affected. That grading matters: mild and moderate cases have a great deal to gain from conservative care, whereas severe compression with constant numbness or visible wasting of the muscle at the base of the thumb is a different situation and needs a surgical opinion.
The evidence for treating this without surgery is stronger than most people expect. A 2024 Cochrane review concluded that surgery probably does not produce a clinically important improvement in symptoms or hand function compared with splinting, and that the overall benefit of surgery remains unclear (Lusa et al., 2024). A 2025 network meta-analysis pooling 49 randomised trials and more than 3,300 patients ranked manual therapy the single most effective conservative treatment for pain in both the short and medium term (Chen et al., 2025).
Perhaps the most useful study for anyone weighing up their options followed 120 patients for four years after being randomly assigned to either manual therapy or surgery. At four years the two groups were equivalent on pain, function and symptom severity, and only 15% of those treated with manual therapy had gone on to have an operation (Fernández-de-las-Peñas et al., 2020). An earlier analysis of the same trial found manual therapy actually outperformed surgery in the first three months and cost less, with less time off work (Fernández-de-las-Peñas et al., 2015; 2019).
We always assess the neck and shoulder as well as the wrist. The nerves that supply your hand begin in the cervical spine and pass through the shoulder and forearm on the way down. Irritation at any point along that route can produce hand symptoms, and when a nerve is compressed in two places at once, a pattern known as double crush, treating only the wrist tends to disappoint. This is one of the more common reasons carpal tunnel treatment fails, and checking for it costs nothing.
Treatment combines mobilisation of the wrist and hand bones to improve the mechanics of the tunnel itself, nerve gliding exercises that restore the median nerve's ability to slide freely through it, soft tissue work to the forearm muscles and treatment of the neck and shoulder where they are contributing. We will usually recommend a neutral wrist splint for sleeping, which addresses the night-time compression directly, alongside practical changes to how you use your hands at work.
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Book OnlineCOMMON SYMPTOMS OF CARPAL TUNNEL SYNDROME
- Numbness or tingling in the thumb, index and middle fingers
- Waking at night with a dead or burning hand
- Shaking or hanging the hand out of bed to relieve symptoms
- Symptoms that spare the little finger
- Pain or aching in the wrist that travels up the forearm
- Weak grip, or dropping cups, keys and phones
- Clumsiness with buttons, zips and other fine tasks
- A swollen feeling in the hand with no visible swelling
- Symptoms brought on by driving, holding a phone or reading
- Wasting or flattening of the muscle at the base of the thumb
Carpal tunnel syndrome responds best when it is caught before the nerve has been compressed for a long time. If your symptoms have moved from occasional night-time tingling to numbness that is present during the day, it is worth having assessed rather than waiting to see whether it settles.
Located on Rivonia Road in Morningside, we treat patients from Sandton, Bryanston, Rivonia, Fourways and across Johannesburg.
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Frequently Asked Questions
Usually not, at least not as a first step. A 2024 Cochrane review found that surgery probably does not produce a clinically important improvement in symptoms or hand function compared with splinting. A separate trial that followed patients for four years found manual therapy and surgery produced equivalent results, and only 15% of the manual therapy group went on to have an operation. Surgery remains the right choice for severe cases, particularly where there is muscle wasting at the base of the thumb or constant numbness that no longer comes and goes.
Night-time numbness is the single most characteristic feature of carpal tunnel syndrome. Most people sleep with their wrists curled, which narrows the tunnel and raises the pressure on the median nerve. Fluid also redistributes when you lie flat. This is why people wake with a dead, tingling hand and shake it to relieve the symptoms. A neutral wrist splint worn at night keeps the wrist straight and is one of the most effective single things you can do.
Mild cases sometimes settle, particularly when there is a clear temporary cause such as pregnancy or a short period of unusually heavy hand use. Established carpal tunnel syndrome usually does not resolve without changing something. The encouraging part is that most mild to moderate cases respond well to conservative treatment, and outcomes are better the earlier it is addressed, before the nerve has been compressed for a long period.
Carpal tunnel syndrome affects the thumb, index finger, middle finger and half the ring finger, because that is the territory of the median nerve. Numbness in the little finger points elsewhere, usually the ulnar nerve at the elbow. Symptoms that involve the whole hand, or that come with neck or shoulder pain, may be coming from the neck rather than the wrist. A proper examination distinguishes between these, which matters because the treatment differs.
They can, and this is missed more often than it should be. The nerves supplying your hand begin in the neck and travel through the shoulder and arm before reaching the wrist. Irritation anywhere along that path can produce hand numbness. There is also a pattern called double crush, where a nerve is compressed at two points at once, typically the neck and the wrist. When the neck is involved and only the wrist is treated, results tend to disappoint.
The approach is more conservative, because pregnancy-related carpal tunnel is usually driven by fluid retention and often resolves on its own after birth. Night splinting, hand positioning advice and gentle manual therapy are the mainstays. Injections and surgery are rarely appropriate during pregnancy. Symptoms that persist well beyond delivery are worth reassessing.
References
- Lusa V, Karjalainen TV, Pääkkönen M, Rajamäki TJ, Jaatinen K. Surgical versus non-surgical treatment for carpal tunnel syndrome. Cochrane Database of Systematic Reviews. 2024;(1):CD001552.
- Chen Y, Han B, Zhang X, et al. Conservative treatments of carpal tunnel syndrome: a systematic review and network meta-analysis. Archives of Physical Medicine and Rehabilitation. 2025;106(9):1447-1458.
- Fernández-de-las-Peñas C, Arias-Buría JL, Cleland JA, et al. Manual therapy versus surgery for carpal tunnel syndrome: 4-year follow-up from a randomized controlled trial. Physical Therapy. 2020;100(11):1987-1996.
- Fernández-de-las-Peñas C, Ortega-Santiago R, de la Llave-Rincón AI, et al. Manual physical therapy versus surgery for carpal tunnel syndrome: a randomized parallel-group trial. Journal of Pain. 2015;16(11):1087-1094.
- Fernández-de-las-Peñas C, et al. Cost-effectiveness evaluation of manual physical therapy versus surgery for carpal tunnel syndrome: evidence from a randomized clinical trial. Journal of Orthopaedic & Sports Physical Therapy. 2019;49(2):55-63.